Jobs in Brighton, MA

About the role

The (Sr) Associate Scientist, Analytical Development will support analytical development and characterization activities for complex biologics, with a focus on virus-like particles (VLPs) and dye-conjugated VLPs. This is a primarily laboratory-based role requiring hands-on experience with molecular biology, electrophoresis, and bioanalytical techniques supporting late-stage clinical drug substance and drug product development. The successful candidate will work closely with Analytical Development scientists to execute analytical testing, support method development, qualification, and transfer activities, maintain high-quality documentation, and ensure laboratory instruments are ready for use. The role also involves collaboration with internal cross-functional teams and external partners, including contract development and manufacturing organizations (CDMOs) and contract research organizations (CROs).

What you'll bring

• Bachelor’s degree in Molecular Biology, Cell Biology, Biochemistry, Biotechnology, Chemistry, Chemical Engineering, or a related scientific discipline.
• 2-4 years of relevant laboratory experience demonstrating hands-on experience with molecular biology techniques, including DNA/RNA extraction, nucleic acid quantification, PCR or qPCR, and agarose gel electrophoresis.
• Experience in aseptic techniques is required with proven experience in regular cell maintenance techniques.
• And performance of cell-based cytotoxicity assays.
• Demonstrated ability to independently execute, document, analyze, and troubleshoot electrophoresis and qPCR experiments.
• Motivation to learn and grow and ability for problem solving is highly desirable.
• Experience with one or more additional analytical techniques, such as SDS-PAGE, Western blotting, capillary electrophoresis, ELISA, UV/Vis spectroscopy, or HPLC/UPLC is preferred.
• Understanding of analytical method development, qualification, validation, and technology transfer principles.
• Experience working in a regulated laboratory environment and applying good documentation and data-integrity practices.
• Experience supporting the analytical development or characterization of biologics, including drug substance and drug product.
• Familiarity with scientific data analysis, graphing software, and basic statistical concepts.
• Some travelling maybe required to assist with assay establishment, troubleshooting at CDMOs

Benefits