Sr Scientist, Antibody Discovery
Quincy, MA On-site
$131,000–$142,600 a yearJobFig found this opening at its original source and checks that it remains available.
About the role
This is an individual contributor role that provides support for bioanalytical characterization for a variety of assays critical for characterizing therapeutic antibody candidates. This role will work closely with our Antibody Characterization and Protein Analytics team at our Quincy, MA location and is responsible for analyzing, optimizing, and troubleshooting a range of workflows, including SPR and BLI affinity analysis, developability assays, flow cytometry, functional assays, and target binding characterization. As an individual contributor Senior Scientist, you will support members of multiple scientific teams as a Project Lead, but will not directly manage team members.
What you'll bring
- Strong knowledge of antibody and biologics characterization is required.
- Previous experience with Carterra SPR systems, Octet BLI, and/or developability assays (HPLC and high throughput plate-based) is required.
- Further direct experience is expected with ELISA, SDS-PAGE, protein quantification, and endotoxin assays.
- Experience in high-throughput assays (1
- Ability to troubleshoot scientific processes, make sound scientific decisions on tight timelines, and accurately analyze and report data with utmost attention to detail.
- Ability to work simultaneously on multiple workflows, prioritizing effectively.
- Effectively communicate project updates, risks, and progress to the manager and cross-functional team members in a timely and professional manner.
- Actively participate in team meetings, clearly articulating needs, concerns, and proposed solutions to drive efficient collaboration.
- PhD in a related technical field with 5+ years of experience in biopharmaceutical analytical development or master's in a. related technical field with 10+ years of experience
- Expert knowledge of antibody biologics characterization assays: extensive hands-on experience required in Carterra SPR, Octet BLI, ELISA, flow cytometry, and antibody developability characterization.
- Advanced understanding of in vivo antibody discovery concepts.
- Strong track record of developing, executing, and analyzing common assay formats for antibody discovery, such as high-throughput screening, epitope binning, ligand blocking analysis, affinity analysis, and cell-based functional assays.