Jobs in Worcester, MA

About the role

The Biotherapeutic and Genetic Medicine (BGM) department at AbbVie is seeking a highly motivated Senior Scientist to join the growing siRNA platform team. In this role, you will work closely with the siRNA synthesis team and cross-functional partners to develop, optimize, and execute analytical methods for the characterization of siRNA and oligonucleotide therapeutics. This individual will serve as the analytical subject matter expert on the siRNA platform, ensuring the delivery of high-quality, well-characterized siRNA materials in support of genetic medicine programs.

What you'll bring

• BS, MS, or PhD in Chemistry, Chemical Biology, Biochemistry, or a related field with typically 0-4+ years (PhD), 8-10+ years (MS), or 10-12+ years (BS) of relevant biotech or pharmaceutical industry experience.
• Hands-on experience with analytical characterization of siRNA, ASO, or related modalities.
• Strong proficiency in HPLC techniques (RP-HPLC, IEX, IP-RP), LC-MS, and UV spectroscopy for oligonucleotide analysis.
• Experience with data analysis software for chromatographic and mass spectrometric data.
• Solid understanding of RNA chemistry, oligonucleotide modifications, conjugation chemistry, and associated analytical challenges.
• Demonstrated ability to independently troubleshoot complex analytical problems and drive continuous method improvement.
• Strong attention to detail, organizational skills, and commitment to data quality and integrity.
• Excellent written and verbal communication skills
• ability to present scientific findings to internal teams.
• Position will be filled at level commensurate with extent of education, experience, and accomplishment - Senior Scientist I or Senior Scientist II

Benefits