Sr. Scientist I (Novel Biologic Entities- Bioanalysis and Translational Science Group- QTAS)
Worcester, MA, United States On-site
$96,500–$183,500 a yearJobFig found this opening at its original source and checks that it remains available.
About the role
The Quantitative, Translational ADME Sciences (QTAS) department at AbbVie is seeking a highly motivated scientist to join the Novel Biologic Entities-Bioanalysis and Translational Science group. The main function of this position is to develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and characterization assays of novel biologics entities. The successful candidate will be experienced in the optimization and implementation of novel and routine LC/MS-based bioanalytical methods for protein and proteome characterization and quantitation to support in vivo PK, TK, and PK/PD studies as well as in vivo stability characterization of complex biotherapeutic modalities. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation. The Quantitative, Translational ADME Sciences (QTAS) department at AbbVie is seeking a highly motivated scientist to join the Novel Biologic Entities-Bioanalysis and Translational Science group. The successful candidate will be experienced in the optimization and implementation of novel and routine LC/MS-based bioanalytical methods for protein and proteome characterization and quantitation to support in vivo PK, TK, and PK/PD studies as well as in vivo stability characterization of complex biotherapeutic modalities. The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
What you'll bring
- ·
- Ph.D. (0+ years), M.S. (8+ years), or B.S. (10+ years) of experience in pharmaceutical or biotechnology industry.
- Highly motivated, self-driven and results-oriented with excellent communication and presentation skills
- capable of working both as a team player and individual contributor.
- Demonstrated ability to manage and analyze data using advanced software tools such as Protein Metrics Byos and GraphPad Prism.
- Passion for generating ideas, learning, solving technical problems, and applying new technologies to advance scientific goals.
- Prior industry experience in drug discovery/development is preferred.
- In-depth understanding of in vivo PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro / in vivo characterization assays is highly desired.
- In-depth understanding of LC-MS methodology with the focus on protein mass spectrometry and hands-on experience with wide range of mass spectrometers, including QQQ, TOF and orbitrap platforms, are highly desired.
- Hands-on experience with proteomics/immunopeptidomics samples preparation as well as automated liquid handling systems is strongly preferred.