Jobs in South San Francisco, CA

About the role

Reporting to the VP, Global Manufacturing & Supply Chain, the Sr. Director External Manufacturing will provide strategic, technical, and operational leadership for all aspects of outsourced manufacturing across drug substance, drug product and packaging/labeling for late-stage development and commercial programs. This role is responsible for end-to-end oversight of CDMO partnerships to ensure reliable, compliant, and cost-effective supply of small molecule APIs and oral solid dose (OSD) products.

What you'll bring

• S. in Chemistry, Chemical Engineering, or related discipline required
• advanced degree (M.S.
• 15+ years of experience in pharmaceutical manufacturing, including significant experience managing external manufacturing and global CDMOs.
• Deep expertise in small molecule manufacturing and oral solid dose (OSD) products.
• Strong understanding of unit operations from API synthesis through drug product manufacturing and packaging & labeling.
• Demonstrated experience supporting late-stage development, PPQ, and commercial product launches.
• Proven track record of CDMO selection, management, and performance optimization.
• Strong knowledge of GMP regulations, validation, CPV, and quality systems.
• Experience working with global manufacturing networks and international CDMOs across multiple time zones.
• Strong technical troubleshooting and problem-solving skills in manufacturing environments.
• Experience with supply chain integration, production planning, and capacity management.
• Excellent leadership, communication, and cross-functional collaboration skills.

Benefits