Sr. Scientist, Immuno-Oncology Research
Cambridge, MassachusettsAll locationsCambridge, MassachusettsResearch On-site
$130,800–$209,400 a yearJobFig found this opening at its original source and checks that it remains available.
About the role
Moderna is looking for a talented and motivated Senior Scientist to focus on discovery, design, and preclinical development of new mRNA-based immunotherapies for cancer. Successful candidates will primarily work with in vitro and ex vivo systems as well as design and analyze in vivo studies to characterize the performance of novel therapeutics. Applicants should be great team members, have a demonstrable track record of independent research accomplishments, and the ability to mentor junior colleagues. The ability to effectively communicate and collaborate with others, as well as a passion for drug discovery are required.
What you'll bring
- Ph.D. in a biological science or B.S/M.S. with extensive relevant experience and at least 2 years industry experience.
- Solid background in immunology, immuno-oncology, and/or tumor biology
- Demonstrated ability to independently design and execute experimental plans for a preclinical drug development program
- Demonstrated ability to work in a fast-paced, highly collaborative and cross-functional team environment
- 5 years of industry experience.
- Expertise in multi-parameter conventional and spectral flow cytometry
- Expertise phenotyping murine, NHP, and human immune cells
- Expertise executing primary immune cell assays and mechanism of action studies
- Experience with biodistribution, pharmacokinetic, and pharmacodynamic analyses using biochemical and flow cytometry assays
- Isolation of nucleic acids from cultured cells and harvested tissue
- Quantification via qPCR, other formats such as bDNA-based approaches
- Isolation of protein lysates from cultured cells and harvested tissue