Jobs in South San Francisco, CA

About the role

This is a contracted position requiring 20-30 hours per week for a 6-month term. The Veterinary Technician / Research Associate will initially be responsible for conducting in vivo rodent studies, with the potential to engage in additional ex vivo or in vitro studies in the Translational Sciences Department to support the advancement of Septerna’s small molecule drug discovery pipeline. The candidate will work independently and collaboratively in an inter-disciplinary setting to execute experiments in preclinical models to understand in vivo pharmacology, establish PK/PD relationships, and inform the efficacy of Septerna’s therapeutic candidates. They will help generate in vivo and/or ex vivo data to determine therapeutic mechanisms of action, in vivo efficacy, and rank candidates for preclinical development. This role is expected to be primarily in the lab with some desk work. Regular weekend working hours will be required. We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will help move therapies through preclinical development, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team on the frontlines of innovative therapeutic development. The position is based in South San Francisco, CA.

What you'll bring

• Demonstrated ability to be hands on and work directly with rodent models, including multiple routes of administration (e.g. oral, subcutaneous, intraperitoneal, intravenous, intramuscular) and sample collection (e.g. tail vein bleeds, jugular bleeds, cardiac puncture, necropsies, etc.).
• Experience working with other scientists to collect and record study data consistently and accurately
• Ability to collaborate and trouble-shoot biological experiments
• Detail-oriented and organized, with strong interpersonal skills for clear and effective communication – ability to proactively engage and collaboration with colleagues
• BSc in Pharmacology, Toxicology, Animal Science, or related biological science
• Experience working with in vitro/ex vivo protein and RNA/DNA assays (e.g. ELISA, qPCR)
• Experience with subcutaneous injections and oral gavage routes of administration
• Experience collecting and processing blood samples, especially timed blood collections
• Experience with cell culture
• Experience with data analysis using Excel and/or Prism
• Experience working with rodent surgical models
• Previous work on therapeutic discovery and development programs in the field of endocrine, inflammatory, neuroscience, or metabolic diseases

Locations