Jobs in South San Francisco, CA

About the role

At AbbVie, we are dedicated to addressing the world’s most complex and serious diseases. Within the Biotherapeutics and Genetic Medicine (BGM) organization, the newly established siRNA team is building and advancing therapeutic programs from early discovery through development, applying rigorous biology, innovative experimental approaches, and data-driven decision-making to deliver differentiated RNA medicines. AbbVie is seeking a highly talented and motivated Senior Scientist I to join our siRNA therapeutics team within BGM at the South San Francisco (ABA) site. The successful candidate will lead in vitro discovery biology efforts to support the development of innovative siRNA-based medicines for oncology. This individual will design and execute experiments, drive scientific innovation, collaborate across multidisciplinary teams, and contribute to advancing therapeutic candidates from early discovery through development candidate nomination for oncology programs. The ideal candidate will possess deep expertise in RNA interference (RNAi) biology and a passion for translating cutting-edge science into transformative medicines. AbbVie is seeking a highly talented and motivated Senior Scientist I to join our siRNA therapeutics team within BGM at the South San Francisco (ABA) site. The successful candidate will lead in vitro discovery biology efforts to support the development of innovative siRNA-based medicines for oncology. The ideal candidate will possess deep expertise in RNA interference (RNAi) biology and a passion for translating cutting-edge science into transformative medicines.

What you'll bring

• Strong hands-on experience with molecular biology techniques (e.g. stem-loop RT-qPCR and RT-qPCR), including assay design, optimization, validation, and data interpretation for siRNA quantification and mRNA target knockdown.
• Extensive experience with mammalian cell culture and transfection techniques.
• Demonstrate ability to learn, understand and master new experimental techniques.
• Strong data analysis and critical thinking abilities.
• Routinely demonstrate scientific initiative and creativity in research or development activities.
• Excellent written and verbal communication skills, attention to detail, multi-tasking and organizational skills, and the ability to collaborate effectively with a team.
• Strong presentation skills with the ability to clearly articulate scientific findings and project updates to project teams, senior leadership, and external stakeholders.
• Highly independent and productive in performing laboratory research or assay development, requiring only minimal direction from or interaction with supervisor.
• Experience working with animal tissues would be a plus.
• Familiarity with tumor intrinsic biology and/or immune oncology.
• Experience working with tumor models would be a plus.
• Experience with extrahepatic oligonucleotide delivery technologies, particularly antibody–oligonucleotide conjugates (AOCs), is highly desirable.

Benefits